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Isotonix Essentials® Turn Down
sku 6702
$72.95
$ 1.46 Cashback
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Primary Benefits* of Isotonix Essentials® Turn Down
Mood, sleep and calmness.
- Helps enhance and stabilize mood
- May promote calmness and relaxation
- Supports healthy sleep quality
- Promotes sleep
- Assists in releasing mental tension
- Helps to clear the mind
- Promotes normal regulation of enzyme and hormone production
- Promotes cognitive health
- Provides antioxidant protections
Mood, Sleep and Calmness
What Makes Isotonix Essentials Turn Down Unique?
It’s hard to feel balanced and grounded sometimes, especially when restless and worrying thoughts cut into your downtime. Sometimes you just need to free yourself from life’s to-do lists and halt the brakes on your ruminating mind. Bring some calmness into your life with Isotonix Essentials®. Designed for relaxation, Isotonix Essentials® Turn Down features a custom blend of vitamins, amino acids and minerals all in one easy-to-use packet. The formula contains effective key ingredients to help you quiet down your body, promote mental clarity, control mental tension and support healthy sleep quality. Many people can benefit from slowing down life a little. According to the American Institute of Stress, 77% of people regularly experience physical symptoms caused by stress (e.g. fatigue, headache, muscle tension); 76% regularly experience psychological symptoms caused by stress.
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.
Product Classifications
Gluten-Free - The finished product contains no detectable gluten (<10ppm gluten)
No Detectable GMOs - The finished product contains no detectable genetically-modified organisms
Vegetarian - This product is vegetarian
Isotonic-Capable Drinkable Supplements - Easy-to-swallow supplements in liquid form are immediately available to the body for absorption
Quality Standards - GMP Operations and Standardized Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Residual Solvents, Potency, Purity and Identity
Directions For Use
![Directions For Use](https://images.shop.com/pim/6702/image_f/5797507USA_ImageF.jpg)
1. Pour contents of packet into a cup.
2. Add 8 fl. oz. of water into the cup and stir.
As a dietary supplement, take once daily or as directed by your healthcare provider. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amounts of water and powder are used.
Key Ingredients
L-Tryptophan
In the body, tryptophan is converted into 5-hydroxytryptophan, which then can be converted into serotonin. The body cannot naturally produce this amino acid; therefore, it must be a part of the diet or ingested through supplementation. Tryptophan is a component of many animal and plant proteins. Food sources of tryptophan are dairy products, beef, poultry, barley, brown rice, fish, soybeans and peanuts.*
Vitamin C (Ascorbic Acid)
Vitamin C is found in peppers (sweet, green, red, hot red and green chili), citrus fruits and brussels sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach, guava, kiwi fruit, currants and strawberries. Nuts and grains contain small amounts of vitamin C. It is important to note that cooking destroys vitamin C activity. Vitamin C is integral in supporting a healthy immune system, promoting cardiovascular health, helping to maintain healthy cholesterol levels and providing an antioxidant defense. The body does not manufacture vitamin C on its own, nor does it store it. Therefore, vitamin C must be acquired through diet and supplementation.*
Potassium (Biocarbonate)
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps maintain fluid balance in the body. It also supports a wide variety of biochemical and physiological processes. Among other things, potassium supports the normal transmission of nerve impulses, contraction of cardiac, skeletal and smooth muscle, synthesis of nucleic acids, maintenance of intracellular tonicity and maintenance of normal blood pressure. In 1928, it was first suggested that high potassium intake could help maintain cardiovascular health. Potassium supports normal muscle relaxation and insulin release. It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes normal heartbeat. Potassium supports the body’s ability to regulate water balance, recover from exercise and eliminate wastes.*
Calcium (Lactate, Carbonate, Sulfate, Citrate)
The highest concentration of calcium is found in milk. Other foods rich in calcium include vegetables such as collard greens, Chinese cabbage, mustard greens, broccoli, bok choy and tofu. Calcium is an essential mineral with a wide range of biological roles. Calcium exists in bone primarily in the form of hydroxyapatite (Ca10 (PO4)6 (OH)2). Hydroxyapatite accounts for approximately 40 percent of bone weight. The skeleton has a structural requisite and acts as a storehouse for calcium. Apart from being a major component of bones and teeth, calcium supports normal muscle contraction, nerve health, heart rhythms, blood coagulation, glandular secretion, energy production and immune system function.* Sufficient daily calcium intake is necessary for maintaining optimal bone density, healthy bones and teeth and has been shown to ease the discomfort of PMS in women. When the body does not get enough calcium per day, it draws calcium from your bones. The amount of calcium in the blood is regulated by PTH (parathyroid hormone). High levels of calcium in the body correlate with normal cardiovascular health and maintaining normal cholesterol levels. In the American Dietetic Association Journal, a study revealed that calcium helped middle-aged women to maintain healthy weight levels.*
Magnesium (Carbonate, Citrate, Glycinate, Oxide)
Magnesium is a component of the mineralized part of bone and supports the normal metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenaline and insulin. It also promotes the normal mobilization of calcium, transporting it inside the cell for further utilization. It plays a key role in supporting the normal functioning of muscle and nervous tissue. Magnesium promotes the normal synthesis of all proteins, nucleic acids, nucleotides, cyclic adenosine monophosphate, lipids and carbohydrates. Magnesium works together with calcium to help maintain the normal regulation of the heart and blood pressure. Importantly, magnesium also supports the body’s ability to build healthy bones and teeth, and promotes proper muscle development. It works together with calcium and vitamin D to help keep bones strong. Magnesium also promotes cardiovascular health by supporting normal platelet activity and helping to maintain normal cholesterol levels.*
Niacin (as Niacinamide)
Niacin plays an essential role as a coenzyme (NAPH/ NADPH) for about 200 enzymes which promote normal tissue respiration, synthesis of fatty acids and steroid hormones, the metabolism of carbohydrates and amino acids, and the transport of hydrogen. When niacin levels are low, the body can use L-tryptophan to manufacture the vitamin. To produce 1 mg of niacin, the body must use 60 mg of L-tryptophan, a process which can rapidly deplete L-tryptophan levels. When niacin levels are sufficient, L-tryptophan can be used for other needs such as retaining healthy levels of serotonin.*
Vitamin B6 (Pyridoxine HCl)
Vitamin B6 promotes the normal conduction of nerve impulses, regulation of steroid hormones, catabolism of glycogen for glucose, heme synthesis, and the synthesis/metabolism of amino acids and neurotransmitters. After conversion to pyridoxal phosphate (PLP), vitamin B6 acts as a cofactor for many enzymatic reactions involving L-tryptophan, including L-tryptophan’s conversion to serotonin.*
Riboflavin (Vitamin B2)
Vitamin B2 is found in liver, dairy products, dark green vegetables and some types of seafood. It serves as a coenzyme, working with other B vitamins. It promotes healthy red blood cell formation, supports the nervous system, respiration, antibody production and normal human growth. It supports healthy skin, nails, hair growth and promotes normal thyroid activity (a healthy thyroid is essential in maintaining a healthy weight, among other things). Vitamin B2 supports the body's ability to turn food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Riboflavin can be useful for pregnant or lactating women, as well as athletes due to their higher caloric needs. Vitamin B2 also promotes the normal breakdown of fats. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily.*
Manganese (Sulfate)
Manganese is a mineral found in large quantities in both plant and animal matter. The most valuable dietary sources of manganese include whole grains, nuts, leafy vegetables and teas. Manganese is concentrated in the bran of grains, which is often removed during processing. Only trace amounts of this element can be found in human tissue. Manganese is predominantly stored in the bones, liver, kidney and pancreas. It supports the normal formation of connective tissue, bones, blood-clotting factors and sex hormones. It supports normal fat and carbohydrate metabolism, calcium absorption and blood sugar regulation. Manganese also promotes normal brain and nerve function. Manganese is a component of the antioxidant enzyme manganese superoxide dismutase (MnSOD). Antioxidants scavenge free radicals that occur naturally in the body but can possibly contribute to the aging process. Antioxidants such as MnSOD can neutralize free radicals. Some experts estimate that as many as 37 percent of Americans do not get the recommended daily amounts of manganese in their diet. This may be due to the fact that whole grains are a major source of dietary manganese, and many Americans consume refined grains more often than whole grains. Refined grains provide half the amount of manganese as whole grains.*
Boron (Citrate)
Boron is a mineral found at high levels in plant foods such as dried fruits, nuts, dark green, leafy vegetables, applesauce, grape juice and cooked dried beans and peas. Boron is found in most tissues, but mainly in the bone, spleen and thyroid. Boron supports normal bone and hormone metabolism. Boron supports the body’s ability to build and maintain healthy bones. It also helps retain adequate amounts of calcium and magnesium to promote proper bone mineralization. Boron is an essential cofactor for the converting vitamin D to its active form. It helps maintain healthy cell membranes, supports proper mental functioning and alertness, and supports normal serum estrogen levels and ionized calcium.*
Vitamin D3 (Cholecalciferol)
Regular sunlight exposure is the main way that most humans get their vitamin D. Food sources of vitamin D include vitamin D-fortified milk (100 IU per cup), cod liver oil and fatty fish such as salmon, and small amounts are found in egg yolks and liver. Vitamin D promotes the absorption of calcium and phosphorus, and supports the production of several proteins involved in calcium absorption and storage. Vitamin D works with calcium to promote strong, hard bones. It supports normal transport of calcium out of the osteoblasts into the extra-cellular fluid and in the kidneys. It also promotes normal calcium and phosphate re-uptake through the renal tubules and intestinal epithelium. It supports normal skin cell growth and helps maintain normal production of insulin by the pancreas.*
Vitamin A (1% as Beta Carotene)
Vitamin A is a fat-soluble vitamin. Sources of vitamin A include organ meats (such as liver and kidney), egg yolks, butter, carrot juice, squash, sweet potatoes, spinach, peaches, fortified dairy products and cod liver oil. Vitamin A is also part of a family of compounds, including retinol, retinal and beta-carotene. All the body’s tissues use Vitamin A for normal growth and repair.*
FAQs
- What does Isotonix mean?
Isotonix dietary supplements are delivered in an isotonic liquid solution. This means that the body has less work to do in the absorption process. The isotonic state of the suspension allows nutrients to pass efficiently into the small intestine and be rapidly delivered into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.* - Who should use this product?
Anyone looking for rest and relaxation support, and those looking for solutions support sleep quality affected by everyday stressors (e.g. travel, occupation, family).* - How do I take Isotonix Essentials Turn Down?
Pour contents of packet into a cup. Add 8 fl. oz of water into the cup and stir. Maximum absorption occurs when taken on an empty stomach. - How often should I use Isotonix Essentials Turn Down?
As a dietary supplement, take once daily or as directed by your healthcare provider. - When should I take Isotonix Essentials Turn Down?
Take this product when you are looking for moments of stress relief and relaxation. - How is Isotonix Essentials Turn Down different from other similar products on the market?
Isotonix Essentials Turn Down knows you need the building blocks to feel refreshed, and that is why we offer a blend of minerals and amino acids that support rest and relaxation.* Our Turn Down formula helps enhance and stabilize your mood, promote mental clarity and support a healthy sleep quality. - Are there any contraindications or warnings for this product?
If you are currently using any prescription medication or have an ongoing medical condition, you should consult your healthcare provider before using this product. Magnesium should be used cautiously in individuals with reduced kidney function due to an increased risk of hypermagnesemia. Discontinue use and consult your healthcare provider if you experience diarrhea, abdominal cramping or discomfort. If you are taking any other sleep aid, monoamine oxidase inhibitors (MAOI) or other antidepressants such as Zoloft or Paxil, psychoactive or tranquilizing drugs such as Klonopin or Valium, or pain medications such as Demerol or Ultram, you should consult your healthcare provider before using this product. Take this supplement separately from prescription drugs. Women who are pregnant or breastfeeding should not use this product. - What is the best way to store this product?
Keep Isotonix stored in a dry, cool place. If Isotonix are stored in the kitchen, keep them away from the stove, sink, heat-generating appliances or window ledges. If you live in a very humid area, you may store Isotonix products in the refrigerator – but not in the fruit and vegetables area.
![FAQs](https://images.shop.com/pim/6702/image_c/5797507USA_ImageD.jpg)
Science
- aan het Rot, M., et al. Social behaviour and mood in everyday life: the effects of tryptophan in quarrelsome individuals. Journal of Psychiatry and Neuroscience. 31(4): 253-262, 2006.
- Baly DL, Schneiderman JS, Garcia-Welsh AL. Effect of manganese deficiency on insulin binding, glucose transport and metabolism in rat adipocytes. J Nutr. 1990; 120:1075-1079.
- Beattie JH, Peace HS. The influence of a low-boron diet and boron supplementation on bone, major mineral and sex steroid metabolism in postmenopausal women. Br J Nutr. 1993 May;69(3):871-84.
- Brilla, L. R., et al. Effect of magnesium supplementation on strength training in humans. J Am Coll Nutr. 11(3):326-329, 1992.
- Cools, R., et al. Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity. Neuropsychopharmacology. 30:1362-1373, 2005.
- Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density on men and women 65 years of age and older. N Engl J Med. 1997; 337:670-676.
- Del-Ben, C., et al. Serotonergic modulation of face-emotion recognition. Brazilian Journal of Medical and Biological Research. 41(4): 263-269, 2008.
- Dietary Reference Intakes for Calcium, Phosphorous, Magnesium, Vitamin D, and Fluoride. Washington, DC: National Academy Press; 1997.
- Durlach J, Durlach V, Bac P, et al. Magnesium and therapeutics. Magnes Res. 1994; 7:313-328.
- Griffiths , W., et al. Tryptophan and sleep in young adults. Psychophysiology. 9(3): 345-356, 1972.
- Gruber H et al. Magnesium deficiency: effect on bone mineral density in the mouse appendicular skeleton. BMC Musculoskelet Disord. 4(1):7, 2003.
- Hartmann, E. and Spinweber, C. Sleep induced by L-tryptophan. Effect of dosages within the normal dietary intake. The Journal of Nervous and Mental Disease. 167(8): 497-499, 1979.
- Huskisson E et al. The influence of micronutrients on cognitive function and performance. J Int Med Res. 35(1):1-19, 2007. Review.
- Hussain S, Ali SF. Manganese scavenges superoxide and hydroxyl radicals: an in vitro study in rats. Neuroscience Letters. 1999; 261:21-24.
- Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes: Calcium, Phosphorus, Magnesium, Vitamin D and Fluoride. National Academy Press. Washington, DC, 1999.
- Keen CL, Ensunsa JL, Watson MH, et al. Nutritional aspects of manganese from experimental studies. Neurotoxicol. 1999; 20:213-223.
- Kobrin SM and Goldfarb S. Magnesium Deficiency. Semin Nephrol. 10:525-35, 1990.
- Martini LA. Magnesium supplementation and bone turnover. Nutr Rev. 1999; 57:227-229.
- Murphy, S., et al. Tryptophan supplementation induces a positive bias in the processing of emotional material in healthy female volunteers. Psychopharmacology ( Berlin ). 187(1): 121-130, 2006.
- Naghii MR, Wall PM, Samman S. The boron content of selected foods and the estimation of its daily intake among free-living subjects. J Am Coll Nutr. 1996 Dec;15(6):614-9.
- New SA et al. Nutritional influences on bone mineral density: a cross-sectional study in premenopausal women. Am J Clin Nutr. 65:1831-9, 1997.
- Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994;102:83-85
- Nielsen FH. Studies on the relationship between boron and magnesium which possibly affects the formation and maintenance of bones. Magnes Trace Elem. 1990;9:61-69
- Nielsen FH. Ultratrace minerals. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease, 9th ed. Baltimore, MD: Williams and Wilkins; 1999:283-303.
- Penland J.G. The importance of boron nutrition for brain and psychological function. Biol Trace Elem Res. 1998; 66:299-317.
- Reid IR, Ames RW, Evans MC, et al. Effect of calcium supplementation on bone loss in postmenopausal women. N Engl J Med. 1993; 328:460-464.
- Rubinsztein, J., et al. Acute dietary tryptophan depletion impairs maintenance of affective set and delayed visual recognition in healthy volunteers. Psychopharmacology. 154: 319-326, 2001.
- Russo, S, et al. Tryptophan as a link between psychopathology and somatic states. Psychosomatic Medicine. 65: 665-671, 2003.
- Ryder K et al. Magnesium intake from food and supplements is associated with bone mineral density in healthy older white subjects. J Am Geriatr Soc. 53(11):1875-1880, 2005.
- Saris NE, Mervaala E, et al. Magnesium: an update on physiological, clinical, and analytical aspects. Clinica Chimica Acta. 294:1-26, 2000.
- Saris N-EL, Mervaala E, Karppanen H, et al. Magnesium. An update on physiological, clinical and analytical aspects (review). Clinica Chimica Acta. 2000; 294:1-26.
- Saris, N.-E. L., et al. Magnesium: an update on physiological, clinical and analytical aspects. Clinica Chimica Acta. 294:1-26, 2000.
- Shils ME. Magnesium. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:169-192.
- Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA. 2000; 283:2822-2825.
- Steritei, R. How to get a good nights sleep with tryptophan. NaturDoctor. 2007. (www.naturdoctor.com/Chapters/Research/Insomnia.pdf)
- Sutherland B, Strong P, King JC. Determining human dietary requirements for boron. Biol Trace Elem Res. 1998 Winter;66(1-3):193-204.
- Talbot JR, Guardo P, Seccia S, et al. Calcium bioavailability and parathyroid hormone acute changes after oral intake of dairy and nondairy products in healthy volunteers. Osteoporosis Int. 1999; 10:137-142.
- Tranquilli AL et al. Calcium, phosphorus and magnesium intakes correlate with bone mineral content in postmenopausal women. Gynecol Endocrinol. 8:55-8, 1994.
- Tucker KL, Hannan MT, Chen H, Cupples LA, Wilson PW, Kiel DP. Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr. 69(4):727-36, 1999.
- Voderholzer, U., et al. Impact of experimentally induced serotonin deficiency by tryptophan depletion on sleep EEG in healthy subjects. Neuropsychopharmacology 18(2): 112-124, 1998.
- Volpe SL, Taper LJ, Meacham S. The relationship between boron and magnesium status and bone mineral density in the human: a review. Magnes Res. 1993;6:291-296
- Vormann J. Magnesium: nutrition and metabolism. Molecular Aspects of Medicine. 24:27-37, 2003.
- Weaver CM, Heaney RP. Calcium. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore, MD: Williams and Wilkins; 1999:141-155.
- Wester PO. Magnesium. Am J Clin Nutr. 45:1305-12, 1987.
- Wolf RL, Cauley JA, Baker CE, et al. Factors associated with calcium absorption efficiency in pre- and perimenopausal women. Am J Clin Nutr. 2000; 72:466-471.
- Yu-Yahiro, J. A. Electrolytes and their relationship to normal and abnormal muscle function. Orthop Nurs. 13(5):38-40, 1994.
Reviews
Displaying 1 - 5 of 49
09/10/2024
by KatelynnM
I can finally sleep!
I have been struggling with sleep for years. I was always up every hour, couldn't get comfortable, and there was no way to get my mind to stop racing. I was able to sleep after the first night of taking Turn down! No more restless nights for me and the taste is great!
09/08/2024
by HannahB
Turn down
I have been taking this product every night for a month now and I absolutely love it it helps my mind calm and helps me sleep so much better
08/30/2024
by JanG
Really helps you get to sleep
Have any of those nights when your brain will just not shut down. I have to many. Turn Down actually calms those thoughts so you can get a good nights sleep. I usually only get 5 to 6 hours of sleep a night so getting to sleep fast is essential. Turn Down to the rescue. I highly recommend this product.
Response from Customer Service
08/31/2024
Thank you for your wonderful review! We're delighted to hear that Isotonix Essentials® Turn Down has been a great help for those nights when your mind just won't quiet down. It's fantastic to know that it effectively calms your thoughts and helps you get to sleep quickly, especially given your limited sleep hours. Your satisfaction and well-being are our top priorities, and we're thrilled to be a part of your nightly routine. If you have any further feedback or need assistance, please don't hesitate to reach out. Thank you for recommending Isotonix Essentials® Turn Down!
08/26/2024
by DUN
Quality Sleep
If I'm getting less than 6 hours of sleep, this is my solution. Turn Down gives me the same energy as a full night's sleep on just a few hours of sleep. It gives that me that good deep sleep. Also tastes good too.
Response from Customer Service
08/28/2024
Thank you for sharing your experience with Isotonix Essentials® Turn Down! We're thrilled to hear that it has become your go-to solution for quality sleep, even when you have less than 6 hours to rest. It's fantastic that Turn Down helps you feel as refreshed as a full night's sleep and provides that deep, rejuvenating rest. We're also glad you enjoy the taste! Your positive feedback means a lot to us. Thank you for being a valued customer and for sharing your wonderful experience with us!
08/22/2024
by Anonymous
WONDERFUL
GREAT TASTE. MY SON THINKS IT IS FUN TO DRINK.
Response from Customer Service
08/23/2024
Dear Valued Customer,
Thank you so much for your feedback! We're thrilled to hear that you and your son are enjoying our nutraMetrix Isotonix Essentials™ Turn Down. We always strive to create flavors that bring joy to our customers. If you have any further comments or questions, please feel free to reach out. Have a wonderful day!
Thank you again!
The Product Information Team
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