• 促進正常的骨骼礦物密度
• 促進動脈的健康 
• 支援免疫系統健康 
• 有助維持骨骼健康 
• 維持正常蝕骨細胞活動以維護骨量
• 幫助維持心血管健康 
• 促進血管彈性 
• 有助維持正常血壓 
• 骨質密度低的女性被發現缺乏維生素K

Isotonix維生素 D（含維生素K2）粉末含有維生素D3（具代謝活性的維生素D形式）和維生素K2（支援血管健康和鈣利用的維生素K形式）。維生素D對於骨骼健康、心臟健康和免疫支援有重要作用；與維生素K共同使用，可支援鈣的正常吸收並促進動脈健康。

Isotonix Vitamin D維生素D是首個以等滲透方式同時提供這兩種強效維生素的產品。Isotonix Vitamin D3 with K2維生素D3（含維生素K2）粉末中加入維生素K是因為維生素K和D配合作用效果顯著，可共同支援鈣的吸收和利用。維生素K支援鈣正常傳輸到骨骼，並促進動脈健康。科學家已發現至少兩種以天然形式存在的維生素K，命名為K1和K2。雖然維生素K的這兩種形式有許多相似之處，但也有一些重要的區別。

維生素K1和K2最顯著的區別在於化學結構，導致它們具有不同的藥動學特性。維生素K1主要存留在肝臟中，高劑量時可能會干擾華法林(warfarin)和其他抗凝血藥物的作用。維生素K2的作用機制不同於K1，它主要傳輸至骨骼和血管。維生素K2有助維持骨量、支援鈣的利用和促進血管彈性。一些研究結論表明維生素K2不會對抗凝血藥物造成影響。*

但是，大多數含有維生素K（包括K1和/或K2）的產品都有警告標示，提醒服用抗凝血藥物的人不要使用此類產品。如果您正在服用華法林或其他抗凝血藥物，在使用任何含有維生素K1或K2的產品前，請先咨詢您的醫護人員。相關詞：維生素D，維生素K，骨骼健康，心血管健康，免疫支援，D3，K2

Key Ingredients found in Isotonix® Vitamin D with K2:

Vitamin D3 (Cholecalciferol): 5000 IU

Vitamin D is a fat-soluble vitamin that is found in some foods and endogenously produced when sunlight strikes the skin and activates vitamin D synthesis. Vitamin D promotes the efficient intestinal absorption of calcium, primarily in the duodenum and jejunum by supporting the synthesis of calcium-binding proteins to promote normal calcium absorption and retention. Vitamin D also promotes the normal formation of bone and normal bone growth and bone remodeling by osteoblasts and osteoclasts. Vitamin D deficiency can be caused by factors such as lack of exposure to sunlight, reduced skin synthesis of vitamin D, lower dietary intake, impaired intestinal absorption, and reduced metabolism to active forms of vitamin D by the kidneys, all of which increase with aging. Deficiency has been linked to numerous health concerns, and insufficient levels of this vitamin are associated with weak bones and muscle weakness. In addition to promoting strong bones, vitamin D also has other roles in health, including supporting the body’s normal modulation of neuromuscular function and immune function. Vitamin D has been shown to support immune-modulation, and it is thought that supplementation promotes immune health by promoting the body’s normal regulation of T-cell function. In reference to cellular health, Vitamin D supports the modulation of many genes that are responsible for encoding proteins that regulate normal cell cycle activity. Vitamin D levels have been strongly correlated to healthy cells. Lastly, through its interaction with VDR (vitamin D receptor), vitamin D supports the healthy expression of the gene encoding renin, thus helping to maintain healthy blood pressure.*

Vitamin K2: 45 mcg

Vitamin K is a fat-soluble vitamin found meat, eggs, dairy and natto. Although a fat-soluble vitamin, the body stores very little K2, and its stores are rapidly depleted without regular dietary intake. Natural vitamin K2, also known as menaquinone-7 (MK-7), is the most bioavailable form of K2 and has the longest half-life in the blood of any form of vitamin K. The Japanese soy food natto is particularly rich in menaquinone-7 (MK-7). Studies of natto consumption in Japan have linked menaquinone-7 to bone and cardiovascular health. The correlation of vitamin K to cardiovascular and bone health directly focuses on supporting proper calcium utilization, whereby adequate metabolism of calcium supports arterial and bone health. This is often referred to as the calcium paradox. The calcium paradox is explained simply as getting calcium in the right place (i.e., into the bone structures instead of the arterial vessel walls). These events are dependent upon the synthesis of the vitamin K-dependent proteins osteocalcin and matrix Gla protein in a process called carboxylation. The carboxylation of these proteins is a post-translational step; that is, osteocalcin and matrix Gla protein are translated from their respective messenger RNA and then modified by enzymes to the active forms. These carboxylated forms support the healthy binding and releasing of calcium. This reaction is essential for optimal and healthy utilization of calcium. Vitamin K2 promotes the synthesis of proteins involved with calcium utilization, thereby supporting bone retention and arterial health. While vitamin D supports the healthy regulation and synthesis of osteocalcin, the mineral-binding capacity of this protein requires vitamin K-dependent carboxylation and is thought to be related to bone mineralization. Gas6 is a vitamin K-dependent protein found throughout the nervous system, as well in the heart, lungs, stomach, kidneys and cartilage. Although the exact mechanism of its action has not been determined, Gas6 appears to be a cellular growth regulator involved in cellular activities such as cell adhesion, cell proliferation and protection against apoptosis.*